Does Chondroitin Really Work?

Chondroitin Joint health is one of the product categories where consumers feel results, or not. It’s also consistently one of the largest selling product categories, with glucosamine and chondroitin combinations leading the pack for years. It’s probably no wonder, given the wide range in chondroitin quality, that consumers often abandon that supplement, citing a lack of results. Why? Let’s look at the details of chondroitin for an answer to that question.

As a veteran participant in the dietary ingredients and supplements market, Synutra has grown with the industry for more than 25 years with a primary focus on chondroitin sulfate materials and related products. Chondroitin sulfate is widely used as a supplement for joint health and comfort. Combined with glucosamine, it is one of the top-5 sellers in the U.S. dietary supplement market. As such, intensive research was needed and numerous clinical studies have been conducted on chondroitin over the years, including the Glucosamine / Chondroitin Arthritis Intervention Trial (GAIT) study conducted by the National Institute of Health, which continues to serve as the most significant scientific study of chondroitin supplementation. In the years since the publication of the GAIT study, the chondroitin sulfate industry underwent explosive growth, numerous branded and generic products emerged, and a massive transformation of its supply chain took place as the supplement became almost ubiquitous.

While numerous independent clinical studies continue to support the benefits and efficacy of chondroitin as a joint health supplement, the industry has in more recent years, experienced issues of sub-standard ingredients and inadequate use of chondroitin in supplements. This in turn, has led to increases in negative customer experiences and in the gradual erosion of customer confidence in joint health and comfort products.

The classic formulation of a typical joint health supplement consists of 1500mg of glucosamine hydrochloride and 1200mg of chondroitin sulfate sodium. Other commonly available formulations include 1500mg chondroitin sulfate sodium alone, a combination of glucosamine, chondroitin sulfate, and MSM, and chondroitin sulfate calcium, along with a number of other formulations that use other complementary ingredients or additives.